Poloxamers: A pharmaceutical excipients with therapeutic behaviors
نویسندگان
چکیده
The effect of excipients for synergistic effect or any combinational therapy is became a one of the best alternative for the dosage form development in the current research. Here we have reviewed on the different category of poloxamers as novel polymer for the drug delivery. Apart from the very good excipient properties, poloxamers showed a clinical and therapeutic uses for cure and treatment of various physiological condition. It is used in the various DNA technology, brain injury, cardiovascular, microbiological, burn injury and ophthalmic treatment also. The goal of this review is to improve the used of poloxamers to achieved economic treatment with less side effect.
منابع مشابه
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Poloxamers, also known as Pluronics®, are block copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), which have an amphiphilic character and useful association and adsorption properties emanating from this. Poloxamers find use in many applications that require solubilization or stabilization of compounds and also have notable physiological properties, including low toxicity...
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